This is the first NFL stadium that I've been to that has comfortable seating on all levels of the stadium. Sat in section 403 for my first game here, that was a Jets/Buffalo Bills game. For the Giants game, I sat here in 144, row 30 when they were playing the Philly Eagles. Row 30 was one of the last few rows but the view was still excellent. I was a little disappointed in the fans in our section. I know New York hates Philly in every sport but come on. Cursing at 21 year old fans when you're 50 years old is just uncalled for. Anyway 144 is nudged kind of in the corner of the end zone. Great alternative to the upper level seats but sitting as close to midfield as possible really enhances your line of sight, that goes for anywhere.
If you're not tailgating, I would always suggest parking at one of the area hotels or other businesses and using their shuttle system to get to the game. I know Redd's restaurant does this and so does the Sheraton hotel. The smart idea would be to take the New Jersey transit from Penn Station to get to the game. Cheaper and quicker that way with virtually no headaches or limit to how many beers one can consume. Go Giants!